Platform for mAb purifications
Therapies based on monoclonal antibodies (mAbs) currently represent the largest and fastest developingbiopharmaceutical market. The [...]
Hydrophobic Interaction Chromatography: Understanding its principle and usage
Discover the fascinating principle behind hydrophobic interaction chromatography and how it is used in scientific [...]
How prepacked chromatography columns help you scale up biomanufacturing effectively
Chromatography is a popular purification technique used in biomanufacturing to separate and isolate your target [...]
Protection of protein A resins during mAb purifications
Today, monoclonal antibodies (mAbs) represent the largest and most progressive biopharmaceutical market. The mAbs used [...]
Effects of elution conditions in the purification of oligonucleotides
Introduction Oligonucleotide synthesis provides custom-made oligonucleotides. The purity of oligonucleotide preparations produced by solid-phase synthesis [...]
Purification of oligonucleotides by anion exchange chromatography
Solid-phase synthesis of oligonucleotides generally give material of rather high purity. However, for many [...]
Conversion of ion-pairing agents/counter ions for oligonucleotides using AIEX
Introduction Efficient purification of therapeutic molecules is of the utmost importance. Equally important, is the [...]
A comparative study of ion exchange vs. ion pair chromatography for preparative separation of oligonucleotides (2025)
The Study: A Comparative Analysis Our study, published in the Journal of Chromatography A, focused [...]
Important optimization parameters for AIEX purifications of 45 nt-long RNA molecules
Introduction RNA molecules have emerged as important molecules in therapeutics, primarily in the form of [...]
